PCD is easy to confuse with cystic fibrosis because the two genetic diseases have similar effects on the lungs. In both disorders, mucus accumulates in patients’ lungs, causing frequent infections and severe congestion. But the roots of the two diseases are different: PCD arises from a malfunction of the cilia, the cellular “brooms” that normally sweep mucus out of the respiratory tract. CF patients, in contrast, have trouble transporting salt and water across cell membranes, causing their bodies to produce abnormally sticky mucus.
https://healthier.stanfordchildrens.org/en/rare-disease-day-pcd-looks-like-cystic-fibrosis-isnt/
The more you know…
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